A method for determining a pre-equalization matrix to be used for testing is provided. A radio communication tester is provided that has a base station emulator and a channel emulator. A device under test is provided that has at least two branches. A N×M multiple-input multiple-output (MIMO) connection is established between the radio communication tester and the device under test. The N×M MIMO connection includes at least two channels. Reference signal received power per branch measurement values are continuously forwarded from the device under test to the radio communication tester. A pre-equalization matrix is determined by the radio communication tester, wherein the reference signal received power per branch measurement values and presence of additive white Gaussian noise (AWGN) are taken into account when calculating the pre-equalization matrix. The pre-equalization matrix compensates cross-talk between the at least two channels and balances the branches such that the device under test receives equal power at its reception antennas. Further, a test setup is described.