An agricultural machine includes a product application system comprising a plurality of actuatable applicator mechanisms, each actuatable applicator mechanism configured to apply a substance on an agricultural surface, an imaging system configured to obtain image data indicative of an image of plant matter on the agricultural surface, and a control system configured to determine a characteristic of the plant matter in an image region defined within the image, control one or more of the actuatable applicator mechanisms to apply the substance on the agricultural surface based on the determined characteristic, and generate a user interface display that displays the image and includes a display element that visually represents the image region within the image.