Disclosed herein are medical device systems, and methods thereof, for automatically detecting access to a medullary cavity. Embodiments include intraosseous access systems with sensing obturators, configured to detect a change in modality, e.g. pressure, oxygen saturation, electrical impedance, etc. at a distal tip thereof. Signals can be transmitted to a control logic that can modify the activation of a driver in response. Signals can be transmitted by way of wired or wireless communication. In an embodiment, signals can be transmitted through conductive polymer material that forms the obturator and allows the obturator to be flexible enough to mitigate accidental needle stick injuries.