A directed jet mouthpiece (10) comprises at least one mouthpiece trough (12, 14) configured to fit over a front portion of a dental arch of a user's teeth. The at least one mouthpiece trough includes a buccal-side vertical member (16), a lingual-side vertical member (18) and an occlusal-side horizontal member (20) extending in between. The at least one mouthpiece trough further includes at least one fluidics inlet (22), a plurality of jet orifices (24) on both buccal- and lingual-side vertical members, and at least one fluidics path (26) disposed between the fluidics inlet and jet orifices. A plurality of directed jet orifices (28) is disposed in end regions (30) of the at least one mouthpiece trough. The at least one fluidics path (26) is further disposed between the fluidics inlet and plurality of directed jet orifices. The plurality of directed jet orifices (28) direct fluid jets rearward towards a remainder of teeth in a user's mouth beyond the end regions (30) of the at least one mouthpiece trough.