Invention Grant
- Patent Title: Pharmaceutical combinations comprising a histone deacetylase inhibitor and epothilone and methods of use thereof
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Application No.: US16344453Application Date: 2017-10-27
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Publication No.: US11998546B2Publication Date: 2024-06-04
- Inventor: Pengyu Huang , Steven Quayle
- Applicant: ACETYLON PHARMACEUTICALS, INC.
- Applicant Address: US MA Boston
- Assignee: ACETYLON PHARMACEUTICALS, INC.
- Current Assignee: ACETYLON PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- International Application: PCT/US2017/058752 2017.10.27
- International Announcement: WO2018/081556A 2018.05.03
- Date entered country: 2019-04-24
- Main IPC: C07D239/28
- IPC: C07D239/28 ; A61K31/337 ; A61K31/426 ; A61K31/427 ; A61K31/505 ; A61P35/00 ; C07D417/06
Abstract:
The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase 6 inhibitor and (b) an epothilone, including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
Public/Granted literature
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