Invention Grant
- Patent Title: Compositions and methods for treating multiple sclerosis
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Application No.: US17189870Application Date: 2021-03-02
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Publication No.: US11998547B2Publication Date: 2024-06-04
- Inventor: Jayakrishna Ambati , Benjamin Fowler , Kameshwari Ambati
- Applicant: University of Kentucky Research Foundation
- Applicant Address: US KY Lexington
- Assignee: University of Kentucky Research Foundation
- Current Assignee: University of Kentucky Research Foundation
- Current Assignee Address: US KY Lexington
- Agency: Stites & Harbison PLLC
- Agent Mandy Wilson Decker
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61P25/16 ; A61P25/28
Abstract:
The present disclosure relates to compounds and compositions that inhibit the NLRP3 inflammasome, for example, a compound according to formula I
wherein
R1 is C1-4 alkyl; and
R2 is H or C1-4 alkyl, provided that when R2 is H. R1 is not CH3.
Also disclosed are methods for treating multiple sclerosis using the compounds and compositions.
wherein
R1 is C1-4 alkyl; and
R2 is H or C1-4 alkyl, provided that when R2 is H. R1 is not CH3.
Also disclosed are methods for treating multiple sclerosis using the compounds and compositions.
Public/Granted literature
- US20210220359A1 Compositions and Methods for Treating Retinal Degradation Public/Granted day:2021-07-22
Information query
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