A topical sanitizing composition for restoring skin's natural balance of bacteria is provided. The topical sanitizing composition includes about 0.02 wt. % to 10.0 wt. % of an active ingredient, at least about 40 wt. % of one or more C1-6 alcohols; and water. The active ingredient comprises one or more of a probiotic, probiotic derivative, and a prebiotic.