Invention Grant
- Patent Title: Messenger RNA therapy for treatment of articular disease
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Application No.: US17117981Application Date: 2020-12-10
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Publication No.: US11998601B2Publication Date: 2024-06-04
- Inventor: Frank DeRosa , Michael Heartlein
- Applicant: TRANSLATE BIO, INC.
- Applicant Address: US MA Lexington
- Assignee: TRANSLATE BIO, INC.
- Current Assignee: TRANSLATE BIO, INC.
- Current Assignee Address: US MA Waltham
- Agency: LATHROP GPM LLP
- Agent James H. Velema, Esq.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K9/127 ; A61K38/17 ; A61K48/00 ; C07K16/00

Abstract:
The present invention provides, among other things, a method of intra-articular delivery of messenger RNA (mRNA), comprising administering into a joint of a subject in need of delivery a composition comprising an mRNA encoding a protein, such that the administering of the composition results in expression of the protein encoded by the mRNA in the joint.
Public/Granted literature
- US20210196820A1 MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE Public/Granted day:2021-07-01
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