Invention Grant
- Patent Title: Therapeutic uses for sodium thiosulfate formulations
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Application No.: US17992703Application Date: 2022-11-22
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Publication No.: US11998604B2Publication Date: 2024-06-04
- Inventor: Alexander Smith
- Applicant: Fennec Pharmaceuticals Inc.
- Applicant Address: US NC Research Triangle Park
- Assignee: Fennec Pharmaceuticals Inc.
- Current Assignee: Fennec Pharmaceuticals Inc.
- Current Assignee Address: US NC Research Triangle Park
- Agency: Knowles Intellectual Property Strategies, LLC
- Main IPC: A61K47/20
- IPC: A61K47/20 ; A61K9/00 ; A61K9/08 ; A61K33/04 ; A61K33/243 ; A61K47/02 ; A61K47/18
Abstract:
Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum-based chemotherapeutics.
Public/Granted literature
- US20230094842A1 ANHYDROUS SODIUM THIOSULFATE AND FORMULATIONS THEREOF Public/Granted day:2023-03-30
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