Invention Grant
- Patent Title: Compounds and methods for selective proteolysis of glucocorticoid receptors
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Application No.: US17047267Application Date: 2019-04-12
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Publication No.: US11998606B2Publication Date: 2024-06-04
- Inventor: James T. Link , Yonathan Lissanu Deribe
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Cynthia Hathaway; Lauren L. Stevens; Erik M. Larsen
- International Application: PCT/US2019/027163 2019.04.12
- International Announcement: WO2019/200217A 2019.10.19
- Date entered country: 2020-10-13
- Main IPC: A61K47/55
- IPC: A61K47/55 ; A61K45/06 ; A61K47/54
Abstract:
The present disclosure relates to steroidal glucocorticoid receptor (GR) ligands and related compositions that degrade the GR and/or modulate its activity that may be utilized as pharmaceuticals for the treatment of diseases including cancer.
Public/Granted literature
- US20210361773A1 COMPOUNDS AND METHODS FOR SELECTIVE PROTEOLYSIS OF GLUCOCORTICOID RECEPTORS Public/Granted day:2021-11-25
Information query
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