Invention Grant
- Patent Title: ASK1 inhibiting agents
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Application No.: US17267631Application Date: 2019-08-13
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Publication No.: US11999715B2Publication Date: 2024-06-04
- Inventor: Felix Gonzalez Lopez de Turiso , Zhili Xin , Martin Himmelbauer , John H. Jones
- Applicant: BIOGEN MA INC.
- Applicant Address: US MA Cambridge
- Assignee: BIOGEN MA INC.
- Current Assignee: BIOGEN MA INC.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- International Application: PCT/US2019/046334 2019.08.13
- International Announcement: WO2020/036949A 2020.02.20
- Date entered country: 2021-02-10
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D405/14

Abstract:
Provided are compounds of Formula (I): Formula (I), including compounds of Formulas (II), (III), (IV), (V) and (VI), wherein X, R1, R2, R3, R4 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorders responsive to the inhibition of apoptosis signal-regulating kinase 1 (ASK1).
Public/Granted literature
- US20210317103A1 ASK1 INHIBITING AGENTS Public/Granted day:2021-10-14
Information query