Invention Grant
- Patent Title: Multispecific antibodies
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Application No.: US16821747Application Date: 2020-03-17
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Publication No.: US11999801B2Publication Date: 2024-06-04
- Inventor: Ulrich Brinkmann , Wolfgang Schaefer , Klaus Mayer
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agency: Morrison & Foerster LLP
- Priority: EP 196046 2014.12.03
- The original application number of the division: US15612104 2017.06.02
- Main IPC: C07K16/46
- IPC: C07K16/46 ; A61K39/395 ; C07K16/28 ; C07K16/30 ; C07K16/32 ; C07K16/44 ; G01N33/53 ; A61K39/00
Abstract:
The present invention relates to multispecific antibodies comprising at least three antigen binding sites wherein the third binding site is disulfide stabilized by introduction of cysteine, method for their production, pharmaceutical compositions containing said antibodies and uses thereof.
Information query
