An intelligent yarn loading system and a control method are provided. The intelligent yarn loading system comprises a twisting machine, a self-walking trolley and a dispatching control system; the twisting machine is provided with a twisting machine wireless communication module for sending a working state of the twisting machine to the dispatching control system; the self-walking trolley is provided with a trolley wireless controller and a self-walking device for receiving an instruction of the dispatching control system and walking to a station of the twisting machine to take off an empty bobbin, and put a basic yarn on a creel of the twisting machine or take off a finished product package for stacking.