System and method for on-loom fabric inspection includes an imaging device collecting images of a weaving area of a loom, a frame grabber receiving images of a fell-pick of and sending compact image data packages to an image processor. Irregularities may be detected by comparing a digital string representing the characteristic sequence of warp-risers and warp-sinkers along the fell-pick with a corresponding row (901) of required warp-risers and required warp-sinkers in a reference matrix (900) representing a required weaving pattern. The digital string may be a sequence of Boolean values.