A downhole tool for cleaning and sealing a wellbore includes a wash tool configured at a downhole end of the downhole tool to generate pulses of a first fluid at a first frequency and a first pressure for washing a target interval of a wellbore. The downhole tool further includes a plugging tool configured uphole or downhole from the wash tool to generate pulses of a second fluid at a second frequency and a second pressure for depositing a sealing plug at the target interval of the wellbore. The second fluid has a higher viscosity than the first fluid, the second frequency is lower than the first frequency, and the second pressure is higher than the first pressure.