Invention Grant
- Patent Title: Compositions and methods for diagnosing and treating peroxisomal diseases
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Application No.: US16477812Application Date: 2018-01-16
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Publication No.: US12000843B2Publication Date: 2024-06-04
- Inventor: Alessandra Biffi , Eleonora Cavalca
- Applicant: CHILDREN'S MEDICAL CENTER CORPORATION , OSPEDALE SAN RAFFAELE S.R.L. , DANA-FARBER CANCER INSTITUTE, INC. , Fondazione Telethon
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation,Ospedale San Raffaele S.R.L.,Dana-Farber Cancer Institute, Inc.,Fondazione Telethon
- Current Assignee: Children's Medical Center Corporation,Ospedale San Raffaele S.R.L.,Dana-Farber Cancer Institute, Inc.,Fondazione Telethon
- Current Assignee Address: US MA Boston; IT Milan; US MA Boston; IT Rome
- Agency: Greenberg Traurig, LLP
- Agent Melissa Hunter-Ensor; Nathan Hsu
- International Application: PCT/US2018/013908 2018.01.16
- International Announcement: WO2018/136434A 2018.07.26
- Date entered country: 2019-07-12
- Main IPC: G01N33/68
- IPC: G01N33/68 ; A61K9/00 ; A61K35/28 ; A61K35/76
Abstract:
The invention features compositions and methods for the treatment and prevention of peroxisomal diseases (e.g., neonatal adrenoleukodystrophy and Zellweger syndrome), including in a subject selected as having increased levels of metallothionein polypeptides. The invention also provides compositions and methods for identifying a subject having a peroxisomal disease involving detecting metallothionein polypeptides or polynucleotides.
Public/Granted literature
- US20200278356A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING PEROXISOMAL DISEASES Public/Granted day:2020-09-03
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