An image segmentation method is provided for an electronic device. The method includes pre-training a first initial model based on a plurality of first sample images to obtain a second initial model, the plurality of first sample images including images of a plurality of human tissues, and the second initial model including distribution information of a plurality of target regions corresponding to the plurality of human tissues, training the second initial model based on a plurality of second sample images to obtain an image segmentation model, image information of the plurality of second sample images including at least distribution information of a plurality of target regions corresponding to a target human tissue reflected in the second sample images, and feeding a first image to the image segmentation model, and segmenting, by using the image segmentation model, the first image according to the image information to output a second image.