Embodiments provide systems and methods to load balance using tenant affinities. A method includes configuring a load balancer with a set of tenant affinities, the set of tenant affinities including a tenant affinity for each of a plurality of tenants with respect to each of a plurality of computing nodes that provide services to users in a multitenant environment. Load balancing may include receiving a user request, associated with a tenant, for a service provided by the computing nodes, determining a highest tenant affinity computing node for the tenant using the set of tenant affinities and directing the user request to the highest tenant affinity computing node for the tenant.