Invention Grant
- Patent Title: DNA-PK inhibitors
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Application No.: US16962442Application Date: 2019-01-16
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Publication No.: US12005127B2Publication Date: 2024-06-11
- Inventor: John Patrick Maxwell , Katrina Lee Jackson , Qing Tang , Mark A. Morris , Steven M. Ronkin , Jinwang Xu , Kevin M. Cottrell , Paul S. Charifson
- Applicant: VERTEX PHARMACEUTICALS INCORPORATED
- Applicant Address: US MA Boston
- Assignee: VERTEX PHARMACEUTICALS INCORPORATED
- Current Assignee: VERTEX PHARMACEUTICALS INCORPORATED
- Current Assignee Address: US MA Boston
- Agency: Barnes & Thornburg LLP
- International Application: PCT/US2019/013788 2019.01.16
- International Announcement: WO2019/143678A 2019.07.25
- Date entered country: 2020-07-15
- Main IPC: C07D239/74
- IPC: C07D239/74 ; A61K48/00 ; C07D239/88 ; C07D239/94 ; C07D401/12 ; C07D403/12 ; C07D417/12 ; C07D491/048
Abstract:
The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various diseases, conditions, or disorders.
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