A foldable display panel and a manufacturing method of the display panel are provided. A plurality of photo spacers are disposed in a first region of the foldable display panel, i.e., the plurality of photo spacers are disposed at a folded position. Widths of the photo spacers gradually decrease from a flexible substrate to a direction away from the flexible substrate. When the foldable display panel is folded, the photo spacers can cooperate with a folding curve to contact with each other, thereby reducing extrusion between the plurality of photo spacers.