Configurable circuits include an input selection region, a computation region, a switching region, and an output region. The input selection region includes a set of input multiplexers and selects and routes input signals. The computation region includes a set of lookup tables, each lookup table being coupled to selected signals from the input selection stage to generate a respective output signal. The switching region includes a set of output multiplexers, each output multiplexer being coupled to output signals from the set of lookup tables to provide circuit outputs responsive to respective output selection signals. The output region includes a domino logic stage, having a set of transistors, coupled to output signals from the set of lookup tables to provide circuit outputs that determine combinations of the signals output by the set of lookup tables.