Disclosed herein is a method of treating diseases and/or disorders associated with the activation of inflammasomes. The method includes administering to a subject in need thereof an effective amount of 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)-carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, a salt, a solvate or an ester thereof.