Invention Grant
- Patent Title: Alpha(v)beta(6) integrin-binding peptides and methods of use thereof
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Application No.: US17504072Application Date: 2021-10-18
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Publication No.: US12023391B2Publication Date: 2024-07-02
- Inventor: Yng Tang , Julie L. Sutcliffe
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Casimir Jones, S.C.
- Agent J. Mitchell Jones
- The original application number of the division: US16217397 2018.12.12
- Main IPC: A61K51/08
- IPC: A61K51/08 ; A61B5/00 ; A61K38/08 ; A61K38/10 ; A61K38/17 ; A61K47/60 ; A61K47/62 ; C07K7/06 ; C07K7/08

Abstract:
The present invention provides peptide conjugates that target an integrin such as αvβ6 integrin. In particular embodiments, the peptide conjugates comprise a moiety such as a PEG moiety, an imaging agent, or a therapeutic agent. The peptide conjugates of the present invention are particularly useful for imaging a tumor, organ, or tissue. Compositions and kits containing the peptide conjugates of the present invention are also provided herein.
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