An insulative packaging for cold chain marketplace. The insulative packaging includes a base unit, a wall unit, and a top unit, which together form an enclosure. Each the base unit, the wall unit, and the top unit has an inflatable liner, one or more insulative sheets, and a radiant barrier. The inflatable liner can be folded and the one or more insulative sheets can be sandwiched between the two folds of the inflatable liner. An article to be protective can be placed within the enclosure and insulative packaging can provide 360-degree insulation and protection.