• Patent Title: Invention of non-homologous peptide sequences to interact with amyloid beta and its precursor protein APP by using computer modeling
  • Application No.: US17090365
    Application Date: 2020-11-05
  • Publication No.: US12024539B1
    Publication Date: 2024-07-02
  • Inventor: Subhajit Dasgupta
  • Applicant: Subhajit Dasgupta
  • Applicant Address: US SC Charleston
  • Assignee: Subhajit Dasgupta
  • Current Assignee: Subhajit Dasgupta
  • Current Assignee Address: US SC Charleston
  • Main IPC: C07K14/00
  • IPC: C07K14/00 G16B5/00
Invention of non-homologous peptide sequences to interact with amyloid beta and its precursor protein APP by using computer modeling
Abstract:
The invented non-homologous peptide sequences are able to form dimers with corresponding amyloid beta (Aβ), its precursor protein (APP) and enzyme gamma secretase (GSA) as observed by using fixed z-axis overlay computer modeling. [The dipole moment values of these dimeric peptide structures are increased with respect to individual Aβ peptide (1-42) and APP fragments].
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