Invention Grant
- Patent Title: Invention of non-homologous peptide sequences to interact with amyloid beta and its precursor protein APP by using computer modeling
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Application No.: US17090365Application Date: 2020-11-05
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Publication No.: US12024539B1Publication Date: 2024-07-02
- Inventor: Subhajit Dasgupta
- Applicant: Subhajit Dasgupta
- Applicant Address: US SC Charleston
- Assignee: Subhajit Dasgupta
- Current Assignee: Subhajit Dasgupta
- Current Assignee Address: US SC Charleston
- Main IPC: C07K14/00
- IPC: C07K14/00 ; G16B5/00

Abstract:
The invented non-homologous peptide sequences are able to form dimers with corresponding amyloid beta (Aβ), its precursor protein (APP) and enzyme gamma secretase (GSA) as observed by using fixed z-axis overlay computer modeling. [The dipole moment values of these dimeric peptide structures are increased with respect to individual Aβ peptide (1-42) and APP fragments].
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