Invention Grant
- Patent Title: Method of treating a tumor expressing carbonic anhydrase IX (G250) by administering a G250-specific chimeric antigen receptor
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Application No.: US17129369Application Date: 2020-12-21
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Publication No.: US12024567B2Publication Date: 2024-07-02
- Inventor: Wayne A. Marasco
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee: DANA-FARBER CANCER INSTITUTE, INC.
- Current Assignee Address: US MA Boston
- Agency: Baker, Donelson, Bearman, Caldwell & Berkowitz, P.C.
- The original application number of the division: US15537780
- Main IPC: C07K16/30
- IPC: C07K16/30 ; A61K35/17 ; A61K38/20 ; A61K39/00 ; C07K14/705 ; C07K14/725 ; C07K16/40 ; C12N5/0783 ; C12N9/88
Abstract:
The present invention provides chimeric antigen receptor cells specific for carbonic anhydrase IX (CAIX) and methods of using same for treatment of CAIX expressing cancers such as renal cell carcinoma.
Public/Granted literature
- US20210221906A1 CARBONIC ANHYDRASE IX SPECIFIC CHIMERIC ANTIGEN RECEPTORS AND METHODS OF USE THEREOF Public/Granted day:2021-07-22
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