Invention Grant
- Patent Title: Modified oligonucleotides targeting SNPs
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Application No.: US16988391Application Date: 2020-08-07
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Publication No.: US12024706B2Publication Date: 2024-07-02
- Inventor: Anastasia Khvorova , Julia Alterman , Faith Conroy , Edith Pfister , Neil Aronin , Ken Yamada
- Applicant: UNIVERSITY OF MASSACHUSETTS
- Applicant Address: US MA Boston
- Assignee: UNIVERSITY OF MASSACHUSETTS
- Current Assignee: UNIVERSITY OF MASSACHUSETTS
- Current Assignee Address: US MA Boston
- Agency: LATHROP GPM LLP
- Agent James H. Velema, Esq.; Michael J. Spellberg, Esq.
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided.
Public/Granted literature
- US20210071177A1 MODIFIED OLIGONUCLEOTIDES TARGETING SNPs Public/Granted day:2021-03-11
Information query
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