Invention Grant
- Patent Title: Methods and compositions for generating dominant short stature alleles using genome editing
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Application No.: US17613115Application Date: 2020-05-28
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Publication No.: US12024711B2Publication Date: 2024-07-02
- Inventor: Sivalinganna Manjunath , Linda A. Rymarquis , Thomas L. Slewinski
- Applicant: MONSANTO TECHNOLOGY LLC
- Applicant Address: US MO St. Louis
- Assignee: Monsanto Technology LLC
- Current Assignee: Monsanto Technology LLC
- Current Assignee Address: US MO St. Louis
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2020/034993 2020.05.28
- International Announcement: WO2020/243361A 2020.12.03
- Date entered country: 2021-11-22
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N9/00 ; C12N9/02

Abstract:
The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through editing of specific subtypes of GA20 oxidase genes to introduce an antisense sequence or segment into the gene. Modified plant cells and plants having a dominant allele reducing the expression or activity of one or more GA oxidase genes are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.
Public/Granted literature
- US20220195445A1 METHODS AND COMPOSITIONS FOR GENERATING DOMINANT SHORT STATURE ALLELES USING GENOME EDITING Public/Granted day:2022-06-23
Information query
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