- Patent Title: N-myristoyltransferase (NMT)1, NMT2 and methionine aminopeptidase 2 overexpression in peripheral blood and peripheral blood mononuclear cells is a marker for adenomatous polyps and early detection of colorectal cancer
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Application No.: US16098948Application Date: 2017-05-03
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Publication No.: US12024748B2Publication Date: 2024-07-02
- Inventor: Shailly Varma Shrivastav , Anuraag Shrivastav
- Applicant: VASTCON
- Applicant Address: CA Winnipeg
- Assignee: Vatscon
- Current Assignee: Vatscon
- Current Assignee Address: CA Winnipeg
- Agency: Ade & Company Inc.
- Agent Michael R Williams; Ryan W Dupuis
- International Application: PCT/CA2017/050538 2017.05.03
- International Announcement: WO2017/190241A 2017.11.09
- Date entered country: 2018-11-05
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; G01N33/573 ; G01N33/574
Abstract:
Described herein is the identification of the NMT1, NMT2 and metAP2 genes, mRNA overexpressed in PBMCs of patients with adenomatous polyps in comparison with patients with non-adenomatous polyps and healthy controls. We also discovered that NMT2 levels are higher in the PBMCs of patients adenomatous polyps in comparison with patients with non-adenomatous polyps and healthy control subjects.
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