A diaphragm pump mechanically operable air pressure regulator assembly that is operable in direct response to the relative operation of an associated diaphragm pump system. The regulator assembly includes a housing that is constructed to receive a static air pressure signal. A cam arrangement is disposed in the regulator housing and is constructed to mechanically cooperate with a shaft of a respective diaphragm pump system. Axial translation of the shaft of the diaphragm pump system effectuates rotation of the regulator cam arrangement. The relative motion of the cam arrangement with respect to the regulator housing manipulates a force associated with a biasing device disposed in the regulator and thereby the relative degree of the static air pressure signal that is communicated to the respective diaphragm pump system.