Systems, devices, and methods related to hybrid basis function, neural network-based digital predistortion (DPD) are provided. An example apparatus for a radio frequency (RF) transceiver includes a digital predistortion (DPD) actuator to receive an input signal associated with a nonlinear component of the RF transceiver and output a predistorted signal. The DPD actuator includes a basis-function-based actuator to perform a first DPD operation using a set of basis functions associated with a first nonlinear characteristic of the nonlinear component. The DPD actuator further includes a neural network-based actuator to perform a second DPD operation using a first neural network associated with a second nonlinear characteristic of the nonlinear component. The predistorted signal is based on a first output signal of the basis-function-based actuator and a second output signal of the neural network-based actuator.