A system and a method for managing a virtual network function (VNF) and a multi-access edge computing (MEC) topology are provided. The method includes the following steps. A first VNF descriptor (VNFD) corresponding to a first VNF is received. According to the first VNFD, first provision data is generated. According to the first VNFD, first internal topology information of the first VNF is generated. According to the first provision data, the first VNF is instantiated to be provisioned. In response to provisioning the first VNF, a graphical user interface including the first internal topology information is output, and the first internal topology information includes a network component communicatively connected to the first VNF.