A system and method for enabling a user to obtain authenticated access to an application using a biometric combination lock. The system is configured for registering a user by receiving a set of biometric expressions and a set of biometric samples of the user, corresponding to two or more biometric factors associated with each biometric expression. Further, the method includes steps of processing the set of biometric samples to compute a Secret-Key (S1) corresponding to the user, generating a Unique-Number (N1) using a random number generation algorithm, applying a Function (F1) to the Secret-Key (S1) and the Unique-Number (N1), to compute a Public-Key (P1).