Invention Grant
- Patent Title: Process for making amino diaryl ethers and amino diaryl ethers hydrochloride salts
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Application No.: US17882432Application Date: 2022-08-05
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Publication No.: US12030855B2Publication Date: 2024-07-09
- Inventor: Michael Bauer , Uwe Hahn , Erhard Bappert
- Applicant: CELLESTIA BIOTECH AG
- Applicant Address: CH Basel
- Assignee: Cellestia Biotech AG
- Current Assignee: Cellestia Biotech AG
- Current Assignee Address: CH Basel
- Agency: Fenwick & West LLP
- Agent Hayan Yoon; Cara A. Mosley
- Priority: EP 179034.6 2018.06.21
- Main IPC: C07D213/62
- IPC: C07D213/62 ; A61K31/44 ; A61P35/00 ; C07D213/61

Abstract:
The present invention relates to a process for making a compound of formula (I) as described herein Formula (I) comprising reducing a compound of formula (II) as described herein with hydrogen in the presence of a palladium catalyst and a solvent wherein the solvent is a polar, aprotic solvent or a C3-C10 alcohol Formula (II). The present invention further relates to a hydrochloride salt and a monohydrochloride salt of the compound of formula (I) as described herein and to a process for making the same Formula (I).
Public/Granted literature
- US20240254084A9 PROCESS FOR MAKING AMINO DIARYL ETHERS AND AMINO DIARYL ETHERS HYDROCHLORIDE SALTS Public/Granted day:2024-08-01
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