Invention Grant
- Patent Title: Hsp90β selective inhibitors
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Application No.: US17055980Application Date: 2019-05-30
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Publication No.: US12030867B2Publication Date: 2024-07-09
- Inventor: Brian Blagg , Sanket Mishra
- Applicant: University of Notre Dame du Lac , University of Kansas
- Applicant Address: US IN South Bend
- Assignee: University of Notre Dame du Lac,University of Kansas
- Current Assignee: University of Notre Dame du Lac,University of Kansas
- Current Assignee Address: US IN South Bend; US KS Lawrence
- Agency: Michael Best & Friedrich LLP
- International Application: PCT/US2019/034672 2019.05.30
- International Announcement: WO2019/232223A 2019.12.05
- Date entered country: 2020-11-16
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61P35/00 ; C07D401/04
Abstract:
Described are compounds of formula (I), based on an isoquinolin-1(2H)-one backbone, that function as Hsp90β selective inhibitors. Also described are pharmaceutical compositions thereof and methods of treating cancer by administering compounds of formula (I).
Public/Granted literature
- US20210269418A1 HSP90 BETA SELECTIVE INHIBITORS Public/Granted day:2021-09-02
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