Invention Grant
- Patent Title: Humanized and affinity matured antibodies to FcRH5 and methods of use
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Application No.: US17514824Application Date: 2021-10-29
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Publication No.: US12030947B2Publication Date: 2024-07-09
- Inventor: Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Clark & Elbing LLP
- Agent Thomas J. Takara
- The original application number of the division: US16395009 2019.04.25
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/40 ; A61K45/06 ; A61K47/68 ; C07K16/28 ; C07K16/30 ; G01N33/574 ; A61K39/00 ; C07K16/00

Abstract:
The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
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