Systems and methods are disclosed for receiving readout requests associated with reading the content of an electronic document by a screen reader application of a client device. In response, an electronic document system applies a document component identification model to the electronic document to generate indicia of at least one conventional segment for conventional readout using left-to-right, top-to-bottom readout and indicia of an unconventional segment to be read out in a manner different from the conventional readout. A document tree, representing a readout sequence, is constructed based on the at least one conventional segment and unconventional segments. The electronic document system provides the document tree to a screen reader, which may perform a readout based on the document tree.