Various embodiments disclosed herein provide for a power control system in a multi-hop integrated access and backhaul network. In the multi-hop integrated access and backhaul network, a donor node can communicate with user equipment devices and relay nodes that have varying power levels; and to avoid receiving uplink transmissions with varying power levels which can impact automatic gain control systems and lower overall throughput, the power control system can manage the power levels of the relay node in order to reduce the difference in power levels. The power control system can schedule relay node devices to transmit uplink transmissions alongside user equipment devices that have a high signal strength; schedule relay nodes and user equipment devices to separate symbols within a time slot; and/or perform closed loop power control management at the relay node to reduce the power level for an uplink transmission.