There is described a system for determining a coronal artery tissue type. The system generally has an optical coherence tomography (OCT) imaging system being configured for acquiring an OCT image of coronal artery tissue; and a controller configured to perform the steps of: using trained feature extraction engines, extracting corresponding feature vectors comprising a plurality of features in at least a region of interest of the OCT image; using trained classification engines, determining corresponding preliminary coronal artery tissue types associated to the region of interest of the OCT image based on corresponding ones of the plurality of feature vectors; and using a majority voting engine, majority voting an output coronal artery tissue type associated to the region of interest of the OCT image based on the previously determined preliminary coronal artery tissue types.