Invention Grant
- Patent Title: Target peptides for immunotherapy and diagnostics
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Application No.: US17170044Application Date: 2021-02-08
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Publication No.: US12042530B2Publication Date: 2024-07-23
- Inventor: Donald F. Hunt , Jeffrey Shabanowitz , Stacy Alyse Malaker , Victor H. Engelhard , Angela L. Ambakhutwala , Kara L. Cummings , Rebecca C. Obeng , Mark Cobbold
- Applicant: University of Virginia Patent Foundation , The University of Birmingham
- Applicant Address: US VA Charlottesville
- Assignee: University of Virginia Patent Foundation,The University of Birmingham
- Current Assignee: University of Virginia Patent Foundation,The University of Birmingham
- Current Assignee Address: US VA Charlottesville; GB Birmingham
- Agency: Jenkins, Taylor & Hunt, P.A.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K35/15 ; A61K35/17 ; A61K39/00 ; A61K45/06 ; C07K16/28 ; G01N33/574 ; G01N33/68

Abstract:
A set of target peptides are presented by HLA A*0101, A*0201, A*0301, B*4402, B*2705, B*1402, and B*0702 on the surface of disease cells. They are envisioned to among other things (a) stimulate an immune response to the proliferative disease, e.g., cancer, (b) to function as immunotherapeutics in adoptive T cell therapy or as a vaccine, (c) facilitate antibody recognition of tumor boundaries in surgical pathology samples, (d) act as biomarkers for early detection and/or diagnosis of the disease, and (e) act as targets in the generation antibody-like molecules which recognize the target-peptide/MHC complex.
Public/Granted literature
- US20230025608A1 TARGET PEPTIDES FOR IMMUNOTHERAPY AND DIAGNOSTICS Public/Granted day:2023-01-26
Information query
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