A brake system for actuating a pair of front wheel brakes and a pair of rear wheel brakes includes a reservoir and a deceleration signal transmitter. First and second power transmission units are configured for selectively providing pressurized hydraulic fluid during a braking event. The first power transmission unit actuates a selected one of the front wheel brakes and a selected one of the rear wheel brakes. The second power transmission unit actuates the other one of the front wheel brakes and the other one of the rear wheel brakes. First and second electronic control units control the first and second power transmission units. A pair of rear brake motors selectively electrically actuate rear wheel brakes. Multiplex control of each of the pairs of front and rear wheel brakes is provided by an arrangement of first and second parallel valves for each wheel brake.