Balanced plug assemblies and pressure regulators having balanced plug assemblies are described herein. A pressure regulator disclosed herein includes a device body defining a fluid passageway between an inlet and an outlet. The device body defines a channel between the fluid passageway and a pressure sense chamber. The pressure regulator includes a seat in the fluid passageway, a stem having a flange, and a plug coupled to the stem. The pressure regulator also includes a stem guide disposed in the channel of the device body. The flange of the stem disposed in a balance chamber of the stem guide and divides the balance chamber into a first balance chamber portion and a second balance chamber portion. The stem guide at least partially forms a balance passage that fluidly couples the pressure sense chamber and the second balance chamber portion.