Invention Grant
- Patent Title: Arginase inhibitors and their therapeutic applications
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Application No.: US17168291Application Date: 2021-02-05
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Publication No.: US12053451B2Publication Date: 2024-08-06
- Inventor: Roman Blaszczyk , Joanna Brzezińska , Anna Gzik , Adam Golebiowski , Julita Nowicka , Bartlomiej Borek , Marek Dziegielewski , Karol Jedrzejczak , Krzysztof Matyszewski , Jacek Olczak
- Applicant: OncoArendi Therapeutics S.A.
- Applicant Address: PL Warsaw
- Assignee: OncoArendi Therapeutics S.A.
- Current Assignee: OncoArendi Therapeutics S.A.
- Current Assignee Address: PL Warsaw
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: PL 7066 2016.05.04
- Main IPC: C07F5/02
- IPC: C07F5/02 ; A61K31/133 ; A61K31/23 ; A61K31/235 ; A61K31/33 ; A61K31/335 ; A61K31/343 ; A61K31/69 ; A61P11/00 ; C07F5/04

Abstract:
Disclosed are small molecule therapeutic compounds that are potent inhibitors of arginase 1 and arginase 2 activity. Also disclosed are pharmaceutical compositions comprising the compounds, and methods for using the compounds for treating or preventing a disease or condition associated with arginase activity.
Public/Granted literature
- US20210260019A1 Arginase Inhibitors and Their Therapeutic Applications Public/Granted day:2021-08-26
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