Invention Grant
- Patent Title: Pharmaceutical combinations comprising a histone deacetylase inhibitor and a CD38 inhibitor and methods of use thereof
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Application No.: US17725234Application Date: 2022-04-20
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Publication No.: US12053468B2Publication Date: 2024-08-06
- Inventor: Steven Norman Quayle , Simon Stewart Jones , Teru Hideshima , Kenneth C. Anderson
- Applicant: Acetylon Pharmaceuticals, Inc.
- Applicant Address: US MA Boston
- Assignee: Acetylon Pharmaceuticals, Inc.
- Current Assignee: Acetylon Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Lathrop GPM LLP
- Agent Brian C. Trinque
- The original application number of the division: US16463247
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/454 ; A61K31/573 ; A61K39/395 ; A61K45/06 ; A61P35/00 ; C07D239/42 ; C07K16/28
Abstract:
The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase inhibitor and (b) a CD38 inhibitor, FIG. 1A including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
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