Invention Grant
- Patent Title: Benzylamino substituted quinazolines and derivatives as SOS1 inhibitors
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Application No.: US17077232Application Date: 2020-10-22
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Publication No.: US12053473B2Publication Date: 2024-08-06
- Inventor: Dirk Kessler , Christiane Kofink , Matthew Russell Netherton , Juergen Ramharter , Tobias Wunberg
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Philip I. Datlow
- Priority: EP 206422 2016.12.22
- Main IPC: A61K31/517
- IPC: A61K31/517 ; A61K9/20 ; A61K31/337 ; A61K31/496 ; A61K31/506 ; A61K31/519 ; A61K31/5377 ; A61K31/7068 ; A61P35/00 ; C07D239/94 ; C07D401/14 ; C07D403/10 ; C07D405/12 ; C07D405/14 ; C07D409/10 ; C07D413/10 ; C07D487/04
Abstract:
The present invention encompasses compounds of formula (I)
wherein the groups R1 to R7 have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.
wherein the groups R1 to R7 have the meanings given in the claims and specification, their use as inhibitors of SOS1, pharmaceutical compositions which contain compounds of this kind and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.
Public/Granted literature
- US20210177851A1 NOVEL BENZYLAMINO SUBSTITUTED QUINAZOLINES AND DERIVATIVES AS SOS1 INHIBITORS Public/Granted day:2021-06-17
Information query
IPC分类:
