Invention Grant
- Patent Title: Substituted tetrahydropyrans as CCR2 modulators
-
Application No.: US17357427Application Date: 2021-06-24
-
Publication No.: US12054484B2Publication Date: 2024-08-06
- Inventor: Junfa Fan , Jaroslaw Kalisiak , Rebecca M. Lui , Venkat Reddy Mali , Jeffrey P. McMahon , Jay P. Powers , Hiroko Tanaka , Yibin Zeng , Penglie Zhang
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA San Carlos
- Assignee: CHEMOCENTRYX, INC.
- Current Assignee: CHEMOCENTRYX, INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Robert Bernstein
- Main IPC: A61K31/35
- IPC: A61K31/35 ; A61K31/453 ; A61K31/4545 ; A61K31/4725 ; A61K31/496 ; A61K31/536 ; A61K31/538 ; A61K31/551 ; A61K31/553 ; A61K45/06 ; A61P35/00 ; A61P37/00 ; C07D309/24 ; C07D405/04 ; C07D405/14 ; C07D413/14 ; C07D471/04
Abstract:
Compounds are provided that are modulators of the CCR2 receptor. The compounds have the general formula (Ia1′):
and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of CCR2 receptors.
and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of CCR2 receptors.
Public/Granted literature
- US20220153733A1 SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS Public/Granted day:2022-05-19
Information query
