Bifunctional molecules recruiting antibodies and targeting cancer cells
Abstract:
The present invention belonging to the technical field of biopharmaceutical discloses bifunctional molecules which are used to recruit antibodies and target tumor cells. The bifunctional molecules in the present invention comprise at least one recruitment moiety capable of binding to the existing antibodies in the body and a targeting moiety capable of selectively binding to the tumor cell. The compounds according to the invention selectively bind to the surface of the cancer cells, and recruit the existing antibodies through the recruitment moiety, and mediate the humoral and cellular immune responses to the cancer cell in the patient. According to this physiological function of the compounds according to the invention, cancer cells can be immunoregulated, which provides a new strategy for tumor immunotherapy.
Information query
Patent Agency Ranking
0/0