Invention Grant
- Patent Title: Universal self-regulating mammalian cell line platform for the production of biologics
-
Application No.: US16622509Application Date: 2018-06-15
-
Publication No.: US12054733B2Publication Date: 2024-08-06
- Inventor: Robert Young , Peter Michael O'Callaghan , Thomas Payne
- Applicant: LONZA LTD
- Applicant Address: CH Visp
- Assignee: LONZA LTD
- Current Assignee: LONZA LTD
- Current Assignee Address: CH Visp
- Agency: MEDLER FERRO WOODHOUSE & MILLS PLLC
- International Application: PCT/US2018/037792 2018.06.15
- International Announcement: WO2018/232265A 2018.12.20
- Date entered country: 2019-12-13
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N9/22 ; C12N15/11 ; A61K39/00
Abstract:
Disclosed are genetic control circuits, cells, and methods that use a repressor polypeptide to reduce the transcription rate of an exogenous therapeutic polypeptide encoding gene in response to a change in condition.
Public/Granted literature
- US20200208171A1 UNIVERSAL SELF-REGULATING MAMMALIAN CELL LINE PLATFORM FOR THE PRODUCTION OF BIOLOGICS Public/Granted day:2020-07-02
Information query
IPC分类:
