Autonomous vehicles including ladders and related methods are disclosed. An example system includes an autonomous vehicle including an integrated ladder and a processor to detect a state of the ladder as being in one of a stowed state, a deployed state, or a use state; in response to detecting that the ladder is in the stowed state, cause the autonomous vehicle to operate in a first drive mode and a second drive mode; in response to detecting that the ladder is in the deployed state, cause the autonomous vehicle to operate in the second drive mode and to restrict from operating in the first drive mode; and in response to detecting that the ladder is in the use state, cause the autonomous vehicle to refrain from operating in the first drive mode and the second drive mode.