The present disclosure relates to an ultrasound elastography system and method. The system may include a transmitting/receiving unit which transmits ultrasound pulses to a target and receives ultrasound echoes from the target to obtain the ultrasound echo signals; an imaging unit which processes the ultrasound echo signals and displays the obtained image; and an analysis unit which detects a region of interest and a shell region selected by an operator in the image, calculate elasticity parameters in a reference region and the shell region respectively, and analyzes the elasticity parameters to obtain an analysis result.